Pharmacogenomics and Herb-Drug Interactions: Merge of Future and Tradition

Drug Interactions, Pharmacogenomics and Cardiovascular Complication

Pharmacogenomics in Drug Discovery and Development

Pharmacogenomics is the study that examines how genetic variations affect the ways in which people respond to drugs. The ways people respond to drugs are complex traits that are influenced by many different genes. Pharmacogenomics intends to develop rational means of optimizing drug therapy, with respect to the patients' genotype, to maximize efficacy with minimal adverse drug reactions. Pharma...

Pharmacogenomics in Personalized Medicine and Drug Metabolism

1 Department of Clinical Pharmacy, School of Pharmacy, Taipei Medical University, No. 250, Wuxing Street, Xinyi District, Taipei 110, Taiwan 2Department of Pharmacy, Taipei Medical University-Wan Fang Hospital, No. 111, Section 3, Xinglong Road, Wenshan District, Taipei 116, Taiwan 3Master Program for Clinical Pharmacogenomics and Pharmacoproteomics, School of Pharmacy, Taipei Medical Universit...

A Conceptual model on the pharmacogenomics implementation complications: An applied qualitative research based on national drug policy components

Introduction: Pharmacogenomics may well have substantial effects on the clinical, economic and regulatory aspects of health sector; which can lead to complications in access. Therefore, there is a need for evidence-based frameworks based on national drug policy components. The objective of the current study is to identify pharmacogenomics-based complications and develop a conceptual model. Mate...

Development of a Pharmacogenomics Model based on Support Vector Regression with Optimal Features Selection Approach to Determine the Initial Therapeutic Dose of Warfarin Anticoagulant Drug

Introduction: Using artificial intelligence tools in pharmacogenomics is one of the latest bioinformatics research fields. One of the most important drugs that determining its initial therapeutic dose is difficult is the anticoagulant warfarin. Warfarin is an oral anticoagulant that, due to its narrow therapeutic window and complex interrelationships of individual factors, the selection of its ...